MEDIT SA

 MEDIT will be presenting at the 2010 Annual Meeting of the American Crystallographic Association, being held in Chicago, July 24-29. Stephane Richard will give a poster presentation titled "Fast and automated functional classification with MEDP-SiteClassifier: an application on purine-binding protein".

MEDIT will be presenting at the ACS spring National meeting, being held in San Francisco, California, USA from  March 21-25, 2010. MEDIT CEO Francois Delfaud will give a  talk.  You will be able to discover and test our software for structure-based and Fragment-based Drug Design in our booth N°119 Hall B.

MEDIT will be presenting at the Structural Biology Conference, being held in Breckenridge, Colorado, USA from  January 8-13, 2010. MEDIT CSO F. Moriaud will give a poster presentation titled "Computational fragment-based approach at PDB scale by protein local similarity".

MEDIT will be presenting at the 5th German Conference on Chemoinformatics, being held in Goslar, Germany from  November 8-10, 2009. MEDIT CSO F. Moriaud will give a poster presentation titled "Computational fragment-based drug design to explore the hydrophobic sub-pocket of the mitotic kinesin Eg5 allosteric binding site"

MEDIT will be presenting at the eCheminfo conference being held in Bryn Mawr College, Philadelphia from 13-16 October 2009, 2009. MEDIT CEO Francois Delfaud will give a  talk.  You will be able to discover and test our software for structure-based and Fragment-based Drug Design in our booth.

MEDIT will be presenting at the Fragment-based Lead Discovery Conference 2009 being held in York, UK  from  Sept. 21 - Sept. 23, 2009. MEDIT CSO Fabrice Moriaud will give a presentation.

MEDIT presents a new work and results on Computational fragment-based drug design to explore the hydrophobic sub-pocket of the mitotic kinesin Eg5 allosteric binding site by using MED-SuMo to retrieve the best fragments and MED-Hybridise to create new ligands. This article is available on: http://www.springerlink.com/content/w524371333636u72/

MEDIT will be presenting at the GRC Computer Aided Drug Design being held in Tilton, NH from  July 19 - July 24, 2009. MEDIT CSO Fabrice Moriaud will give a  poster presentation.

MEDIT will be presenting at the CHI Structure-Based Drug Design Conference being held in the Royal Sonesta Hotel, Boston, MA, from june 4 to june 5 2009. You will be able to discover and test our software for structure-based and Fragment-based Drug Design in our booth.

MEDIT will be presenting at the CHI Fragment-Based Techniques being held in Hilton San Diego Resort, San Diego, CA, from April 7 to April 8 2009. You will be able to discover our latest release in our booth for MED-SuMo, MED-Hybridise and pipeline pilot component.

Sanofi-Aventis decides to use MED-Fragmentor to build the database of MED-Portions (protein-fragments structural object) and MED-Hybridise technology to rationally generate fragment-based chemical compounds by crossing the PDB and chemical supplier databases.

ICSN decided to use MED-SuMo technology to enhance its work on protein characterization and highlight structural links between proteins. MED-SuMo is a powerful molecular modelling software to compare surface interactions in few minutes toward the PDB (comparison in term of chemical features and shape).

MEDIT will be presenting at the eCheminfo Community of Practice InterAction Meeting PA from 2008 October 13 to 17. MEDIT CSO Fabrice Moriaud will give a presentation titled "Exploration of the Chemical Diversity Generated by the Hybridisation of PDB Ligands" during the PDB Ligands: Analysing their Structure & Binding Data session.

Dr Charles Andrianjara from Pierre Fabre laboratories will give a presentation on the results of the CARRIOCAS project wich involves MEDIT and Pierre Fabre laboratories titled "Chemogenomic Space Exploration: Use of MED-SUMO Tools to Analyse Target and Ligand Space of the Kinome" during the In Silico based Chemogenomics session.

 Under the terms of the agreement, MEDIT will apply its molecular modelling expertise on two MUTABILIS targets to provide affinity model to optimise MUTABILIS' proprietary molecules for their anti-infective programs.

MEDIT will be presenting at the 236^th ACS National Meeting & Exposition being held in Philadelphia, PA from 2008 August 17 to 21. MEDIT CEO François Delfaud will give a presentation titled "A fragment-based computational protocol upon PDB to fragment library design, lead discovery and lead optimization" during the Computational Approaches for Fragment Screening session of the conference (Division of Computers in Chemistry).

MEDIT will be demonstrating at the eCheminfo workshop on Drug Discovery & Planning Methods, a Hands-On Practice Approach, being held in Oxford University, Oxford, U.K.  from  July 21 - July 25, 2008. MEDIT CSO F. Moriaud will give a hands-on sessions titled "Discover MED-Hybridise for innovative Fragment-based Drug Design at PDB scale" Tuesday July 22nd 9.00-12.30 AM

MEDIT will be presenting at the CHI Structure-Based Drug Design Conference being held in the World Trade Center, Boston, MA, from june 25 to june 27 2008. You will be able to discover our latest development in our booth: MED-SuMo, MED-Hybridise Lead discovery and  MED-Hybridise Lead optimization and pipeline pilot component.

The MEDIT SA website has evolved  from medit.fr to medit-pharma.com on June 27th 2008. The website is entirely new and includes our recent developments (2007/2008) around lead discovery and lead optimization.

Please visit applications for MED-SuMo and for our new software MED-Hybridise

MEDIT will be presenting at the Accelrys 2008 Science & Technology Forums, being held in Paris, France the june 12th, 2008. MEDIT Application scientist  L. Martin will give a presentation titled "MED-SuMo to mine the interaction surfaces in the PDB: Integration in Pipeline Pilot". The abstract of the talk is: 
"Take advantage of the structural information in the PDB and study protein interaction surface with MED-SuMo. Use our fragment database coming from PDB ligands to populate the query binding sites according to structural similarity. Then design new potential ligands with MED-Hybridiser. Here, we will show an application of both software combined to Pipeline Pilot components for Lead Discovery."

MEDIT will be presenting at the 8th International Conference on Chemical Structures being held in Noordwijkerhout, The Netherlands, from 2008 from june 1 to june 5. MEDIT CSO F. Moriaud, will give a presentation titled "A fragment-based computational protocol at PDB scale - Application to lead-optimization of DFG-out kinase inhibitors" during the Structure-Based Drug Design and Virtual Screening session of the conference.

MEDIT has joined others software editors in the Accelrys Independent Software Vendors (ISV) partner program.

This first release consists of three modules: MED-SuMo server, MED-Hybridise Lead discovery and  MED-Hybridise Lead optimization. The modules facilitate our target based ligand generation protocol: populating a binding site with 3D fragments and generating/optimizing leads.

   MED-SuMo component

   MED-Hybridise for lead discovery

   MED-Hybridise for lead optimization

MEDIT will be presenting at the Computer Aided Drug Design Keystone Symposia, being held in Steamboat Springs, Colorado from  March 29 - April 3, 2008. MEDIT CEO F. Delfaud will give a poster presentation titled "A fragment-based computational protocol upon PDB to explore multiple binding pockets: Application to scaffold decoration"

Driven by Bull, the POPS project aims at developing high-performance computing systems up to 1 PetaFlops (10¹⁵ operations per second). MEDIT is classifying all binding sites from the PDB structures using the Multi Comparison Mode of MED-SuMo